After standing in as best man for his longtime friend Carl Petersen, Randy Dupree loses his job, becomes a barfly and attaches himself to the newlywed couple almost permanently -- as their houseguest. But the longer Dupree camps out on their couch, the closer he gets to Carl's bride, Molly, leaving the frustrated groom wondering when his pal will be moving out.
Owen Wilson
Dupree
Kate Hudson
Molly
Matt Dillon
Carl
Michael Douglas
Mr. Thompson
Seth Rogen
Neil
Amanda Detmer
Annie
Ralph Ting
Toshi
Todd Stashwick
Tony
Bill Hader
Mark
Lance Armstrong
Lance Armstrong
Jason Winer
Eddie
Sidney S. Liufau
Paco
Billy Gardell
Bartender Dave
Eli Vargas
Aaron
Houston Mack
Dougie
