A masked villain wreaks mayhem on the city of Coolsville with a monster machine that creates real-life versions of Mystery Inc.'s former foes like The 10,000 Volt Ghost, The Cotton Candy Glob, The Skelemen and The Pterodactyl Ghost. Fred, Daphne, Shaggy, Velma and Scooby-Doo launch an investigation into the monster outbreak that leaves Shaggy and Scooby questioning their roles in Mystery Inc. Eager to prove their detective skills, the ever-ravenous duo comes up with a secret plan to solve the mystery all by themselves. Can the gang unravel their most challenging case?
Freddie Prinze Jr.
Fred
Sarah Michelle Gellar
Daphne
Matthew Lillard
Shaggy
Linda Cardellini
Velma
Neil Fanning
Scooby-Doo Voice / Tasmanian Devil (voice)
Seth Green
Patrick
Peter Boyle
Old Man Wickles
Tim Blake Nelson
Jacobo
Alicia Silverstone
Heather
Pat O'Brien
Pat O'Brien
Bill Meilen
Chauffeur
Zahf Paroo
Ned
Chris Gauthier
Daphne's Tattooed Fan #1
Peter New
Daphne's Tattooed Fan #2
Morgan Brayton
Mullet Nerdette #1
